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Key Documents

810891C

Avanti

DSPE PEG(2000)-N-Cy5

Avanti Research™ - A Croda Brand, chloroform solution

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]-N-(Cyanine 5)

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About This Item

Empirical Formula (Hill Notation):
C164H299N4O55P
CAS Number:
2315262-02-1
Molecular Weight:
3238.10
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

99% (TLC)

form

chloroform solution

packaging

pkg of 1 × 1 mg (
810891C-1MG)
pkg of 5 × 1 mg (
810891C-5MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (810891C-1MG)
1 mg/mL (810891C-5MG)

shipped in

dry ice

storage temp.

−20°C

Application

DSPE PEG(2000)-N-Cy5 is suitable for use to ensure the proper insertion of folic acid to red blood cells (RBCs) membrane by fluorescence microscopy.

Biochem/physiol Actions

DSPE PEG(2000)-N-Cy5 is used in the preparation of folic acid and Cy5 modified red blood cells (RBCs) vesicles (FRVs). DSPE PEG(2000)-N-Cy5 is used to demonstrate the modification of RBCs membrane with folic acid. After mixing DSPE PEG(2000)-N-Cy5 with RBC, the non-luminous membrane exhibits bright Cy5 fluorescence, enables visualization with fluorescence microscope.

Packaging

5ML Clear Glass Sealed Ampule (810891C-1MG)
5ML Clear Glass Sealed Ampule (810891C-5MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Engineered red blood cells for capturing circulating tumor cells with high performance
Zhu DM, et al.
Nanoscale, 10(13), 6014-6023 (2018)
Erythrocyte derived vesicles for circulating tumor cells capturing and specific tumor imaging
Liu A, et al.
Nanoscale, 11, 12388-12396 (2019)
Ming Chen et al.
Nanoscale, 11(25), 12388-12396 (2019-06-20)
The precise diagnosis of cancer remains a great challenge; therefore, it is our research interest to develop safe, tumor-specific reagents. In this study, we designed nanovesicles derived from erythrocyte membranes; the nanovesicles are capable of recognizing tumor cells for both

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