810209X

C6-NBD Ceramide

Avanti Polar Lipids 810209X

• Synonym(s): N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine:methanol (8:2)
• Empirical Formula (Hill Notation): C₃₀H₄₉N₅O₆
• CAS Number: 94885-02-6
• Molecular Weight: 575.74
• UNSPSC Code: 12352211

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (810209X-1mg)
• manufacturer/tradename: Avanti Polar Lipids 810209X
• concentration: 1 mg/mL (810209X-1mg)
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
• InChI key: HZIRBXILQRLFIK-VPZZKNKNSA-N

Description

General description

C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.

Application

C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.

Biochem/physiol Actions

Sphingolipid metabolism yields ceramide as one of the products. The family of ceramide synthases catalyses its synthesis. The ceramides differ in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (810209X-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H302 + H312 - H315 - H319 - H331 - H336 - H351 - H361d - H370 - H372
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P311 - P308 + P311
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 1 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3