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Sigma-Aldrich

Gold nanoparticles

20 nm diameter, OD 1, stabilized suspension in citrate buffer

Synonym(s):

Au NP, Gold Colloid

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About This Item

MDL number:
MFCD00003436
UNSPSC Code:
12352302
PubChem Substance ID:
329765544
NACRES:
NA.23

form

nanoparticles
suspension

contains

Proprietary Surfactant as stabilizer

concentration

~6.54E+11 particles/mL

OD

1

diameter

20 nm

λmax

518-522 nm

PDI

<0.2

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles (AuNPs) are versatile materials widely used in biomedical sciences and electrochemical sensor based applications. AuNPs are tunable nano-materials with excellent thermo-mechanical properties, high surface area, and low toxicity.

Application

Citrate stabilized AuNPs can be used for a variety of applications such as:
  • neutrophil labeling for monitoring the effect of different drugs
  • immobilization of proteins for biosensor applications
  • nano-carrier for drug delivery system for the release of hydrophobic drugs.

Ideal for adsorption of thiolated ligands such as oligonucleotides and polyethylene glycols. Also, due to the increased stability, these gold nanoparticles are ideal for use in physical and optical applications. Note: This product is not ideal for protein adsorption. For gold nanoparticles suitable for adsorption of proteins and other ligands for conjugate development, please see our gold nanoparticles stabilized in PBS.

This material is highly monodisperse (<12% variability in size and shape), and provides significantly improved surface reactivity. Applications include Surface Enhanced Raman Lables, Sensing/Detection, Biological Targeting, Plasmonics and Electronics.

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gold nanoparticles in delivery applications
Ghosh P, et al.
Advanced Drug Delivery Reviews, 60(11), 1307-1315 (2008)
Gold-Organic-Inorganic High-Surface-Area Materials as Precursors of Highly Active Catalysts
Budroni G and Corma A
Angewandte Chemie (International ed. in English), 45(20), 3328-3331 (2006)
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
Alkilany AM and Murphy CJ
Journal of Nanoparticle Research, 12(7), 2313-2333 (2010)
Biomedical applications of gold nanoparticles
Cabuzu D, et al.
Current Topics in Medicinal Chemistry, 15(16), 1605-1613 (2015)
Design of hybrid multimodal poly (lactic-co-glycolic acid) polymer nanoparticles for neutrophil labeling, imaging and tracking
Qiu Y, et al.
Nanoscale, 5(24), 12624-12632 (2013)
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