637963

3,7-Dimethyloctylmagnesium bromide solution

1.0 M in diethyl ether

• Synonym(s): Bromo(3,7-dimethyloctyl)magnesium
• Empirical Formula (Hill Notation): C₁₀H₂₁BrMg
• CAS Number: 114499-45-5
• Molecular Weight: 245.48
• MDL number: MFCD06798074
• UNSPSC Code: 12352103
• PubChem Substance ID: 24882899
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• Quality Level: 100
• concentration: 1.0 M in diethyl ether
• density: 0.856 g/mL at 25 °C
• SMILES string: CC(C)CCCC(C)CC[Mg]Br
• InChI: 1S/C10H21.BrH.Mg/c1-5-10(4)8-6-7-9(2)3;;/h9-10H,1,5-8H2,2-4H3;1H;/q;;+1/p-1
• InChI key: CZIGPVDHJSGGIU-UHFFFAOYSA-M

Description

Application

• Evaluating how cationic lipid affects mRNA-LNP physical properties and biodistribution: This study describes the synthesis process where 3,7-Dimethyloctylmagnesium bromide was used as a reagent in the preparation of a lipid component for lipid nanoparticles (LNPs), which are crucial in mRNA delivery systems (Gueguen et al., 2024).

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H224 - H302 - H314 - H336
• Precautionary Statements: P210 - P233 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P403 + P233
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH014 - EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): -13.0 °F - closed cup
• Flash Point(C): -25 °C - closed cup