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404624

Sigma-Aldrich

3-Aminopyrrolidine dihydrochloride

98%

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About This Item

Empirical Formula (Hill Notation):
C4H10N2 · 2HCl
CAS Number:
Molecular Weight:
159.06
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

mp

>300 °C (lit.)

SMILES string

Cl[H].Cl[H].NC1CCNC1

InChI

1S/C4H10N2.2ClH/c5-4-1-2-6-3-4;;/h4,6H,1-3,5H2;2*1H

InChI key

NJPNCMOUEXEGBL-UHFFFAOYSA-N

General description

3-Aminopyrrolidine dihydrochloride (3-pyrrolidinamine dihydrochloride) is one of the key intermediate of tosufloxacin and other quinolone antibiotics.

Application

3-Aminopyrrolidine dihydrochloride is the suitable reagent used as an internal standard for the quantitative analysis of amino acids in bio-fluids. (R,S) 3-Aminopyrrolidine dihydrochloride may be used in the preparation of cis-[PdCl2(pyrr)] and cis-[PtCl2(pyrr)] (pyrr= (R,S)-3-aminopyrrolidine) complexes.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis of 3-Aminopyrrolidine and its N-alkylating Derivatives [J].
Run-pu SHEN, et al.
Journal of Chemical Engineering of Chinese Universities / Gao Xiao Hua Xue Gong Cheng Xue Bao, 4, 014-014 (2003)
Pd (II) and Pt (II)(R, S)-3-aminopyrrolidine complexes. Reactions with 9-ethylguanine and study of their antiproliferative activity.
Riera X, et al.
Inorgorganica Chimica Acta, 339, 253-264 (2002)
Jieyu Zhao et al.
Journal of proteome research, 15(2), 468-476 (2016-01-20)
The interaction between carbon (C) and nitrogen (N) metabolism can reflect plant growth status and environmental factors. Little is known regarding the connections between C-N metabolism and growing regions under field conditions. To comprehensively investigate the relationship in mature tobacco
Shahlizah Sahul Hamid et al.
Planta, 249(6), 1921-1947 (2019-03-21)
Among seaweed groups, brown algae had characteristically high concentrations of mannitol, and green algae were characterised by fructose. In red algae, metabolite profiles of individual species should be evaluated. Seaweeds are metabolically different from terrestrial plants. However, general metabolite profiles
Shuxin Liu et al.
Scientific reports, 7(1), 8150-8150 (2017-08-16)
Uremia has been a rapidly increasing health problem in China. Hemodialysis (HD) is the main renal replacement therapy for uremia. The results of large-scale clinical trials have shown that the HD pattern is crucial for long-term prognosis of maintenance hemodialysis

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