217808
cis-Aconitic anhydride
95%
Synonym(s):
cis-Propene-1,2,3-tricarboxylic anhydride
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C6H4O5
CAS Number:
Molecular Weight:
156.09
Beilstein:
127575
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Assay
95%
mp
75-78 °C (lit.)
SMILES string
OC(=O)CC1=CC(=O)OC1=O
InChI
1S/C6H4O5/c7-4(8)1-3-2-5(9)11-6(3)10/h2H,1H2,(H,7,8)
InChI key
GVJRTUUUJYMTNQ-UHFFFAOYSA-N
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Ahmad et al.
Anticancer research, 10(3), 837-843 (1990-05-01)
Daunorubicin (DNR) was coupled to monoclonal antibodies (Mab) reactive to breast tumor cells using the acid-labile linking agents cis-asonitic anhydride and two other non acid-labile analogs, glutaric anhydride and citraconic anhydride. The acid derivatives of DNR formed by reaction with
J A Kamps et al.
Biochimica et biophysica acta, 1278(2), 183-190 (1996-01-31)
Human serum albumin (HSA) derivatized with cis-aconitic anhydride (Aco-HSA) that was earlier shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1), was covalently coupled to conventional liposomes, consisting of phosphatidylcholine, cholesterol and maleimido-4-(p-phenylbutyryl)phosphatidylethanolamine, using the heterobifunctional reagent N-succinimidyl-S-acetylthioacetate
Abhijeet Pandey et al.
Materials science & engineering. C, Materials for biological applications, 98, 419-436 (2019-03-01)
In the present investigation, FePt alloy nanoparticles were synthesized with controlled size and elemental composition followed by surface modification using (3-Aminopropyl) triethoxysilane (APTES). Lenalidomide was covalently bound to FePt-NH2 by pH sensitive hydrazone bonding. Hyaluronic acid was conjugated to amino
Jinbiao Gao et al.
Colloids and surfaces. B, Biointerfaces, 174, 416-425 (2018-11-28)
Ultrasound-triggered delivery system is among the various multifunctional and stimuli-responsive strategies that hold great potential as a robust solution to the challenges of localized drug delivery and gene therapy. In this work, we developed an ultrasound-triggered delivery system PFP/C9F17-PAsp(DET)/CAD/PGA-g-mPEG nanodroplet
K L Law et al.
Anticancer research, 10(3), 845-852 (1990-05-01)
Antibody-drug conjugates containing a linkage susceptible to lysosomal hydrolases were constructed by coupling peptide-daunorubicin (DNR) derivatives to MAb. Using a modification in the method of Trouet et al, peptide derivatives of DNR containing the sequences Ala-Leu and Ala-Leu-Ala-Leu linked to
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