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159158

Sigma-Aldrich

Acetamidine hydrochloride

95%

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About This Item

Linear Formula:
CH3C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
94.54
Beilstein:
3591762
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

solid

mp

165-170 °C (lit.)

functional group

amidine

SMILES string

Cl[H].CC(N)=N

InChI

1S/C2H6N2.ClH/c1-2(3)4;/h1H3,(H3,3,4);1H

InChI key

WCQOBLXWLRDEQA-UHFFFAOYSA-N

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General description

Acetamidine hydrochloride is an amidine salt and its conversion to 2,4,6-trimethyl-sym-triazine has been studied.

Application

Acetamidine hydrochloride was used in the preparation of decarboxyectoine. It was also used in the synthesis of ethyl 4-(4-hydroxyphenyl)methylidene-2-methyl-5-oxo-1-imidazolacetate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of the sym-Triazine System. I. Trimerization and Cotrimerization of Amidines.
Schaefer FC, et al.
Journal of the American Chemical Society, 81(6), 1466-1470 (1959)
H Niwa et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(24), 13617-13622 (1996-11-26)
The jellyfish Aequorea victoria possesses in the margin of its umbrella a green fluorescent protein (GFP, 27 kDa) that serves as the ultimate light emitter in the bioluminescence reaction of the animal. The protein is made up of 238 amino
Michael Schnoor et al.
Biochemical and biophysical research communications, 322(3), 867-872 (2004-09-01)
Different substances such as dimethyl sulfoxide, tetramethylene sulfoxide, 2-pyrollidone, and the naturally occurring compatible solute betaine enhance PCR amplification of GC-rich DNA templates with high melting temperatures. In particular, cyclic compatible solutes outperform traditional PCR enhancers. We therefore investigated the
Four-component synthesis of fully substituted 1,2,4-triazoles.
Steven T Staben et al.
Angewandte Chemie (International ed. in English), 49(2), 325-328 (2009-12-10)
J A Doebler
Cell biology and toxicology, 15(5), 279-289 (2000-05-17)
Studies were conducted using a novel in vitro approach to investigate the efficacy of acetamidine hydrochloride (ACE) and guanidine hydrochloride (GUAN), previously shown to block gramicidin D (GRAM) channels in artificial membranes, in preventing the toxic effects of GRAM in

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