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54240-U

Supelco

Supel-Select SCX SPE Tube

bed wt. 30 mg, volume 1 mL, pk of 100

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About This Item

UNSPSC Code:
41115712
NACRES:
NB.21

material

PE frit (20 μm)
polypropylene hardware

quality

MS Friendly

composition

bed wt., 30 mg

packaging

pk of 100

technique(s)

solid phase extraction (SPE): suitable

surface area

160-420 m2/g

volume

1 mL

matrix

Sulfonic acid functionalized hydrophilic modified styrene polymer particle platform

matrix active group

sulfonic acid phase

particle size

50-70 μm

pore size

80-200 Å pore size

application(s)

food and beverages

separation technique

ion exchange

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General description

Retention Mechanism: Ion-Exchange
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

  • Sulfonic acid functionalized hydrophilic modified styrene polymer
  • Developed for the extraction of a highly broad range of compounds from aqueous samples
  • Retention predominately based on ion-exchange; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.

View related article: Isolation and LC-MS Characterization of Illicit Bath Salts in Urine

Features and Benefits

  • Excellent sample prep performance at a lower price
  • Amenable to generic methodology - save time, money, and headache during method development
  • Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing
  • Resistance to overdrying allows for more robust methdology
  • Low UV and MS extractables for lower background and greater sensitivity
  • Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.

SPE retention mechanism in this case is based on the electrostatic attraction of charged functional groups of the analyte(s) to oppositely charged functional groups on the sorbent.

Protocols

Separation of 3,4-Methylenedioxypyrovalerone HCl (MDPV) solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Buphedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 3-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Butylone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Ethylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 4-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Mephedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Retention occurs through polar interaction between the sorbent and analytes. Typical sample matrices that can be employed in normal-phase SPE include hydrocarbon or fatty oils diluted in a solvent like hexane, isooctane, chlorinated solvent, THF, diethyl ether, or ethyl acetate.

Chromatograms

application for HPLC

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