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49055

Supelco

Parathion-methyl

PESTANAL®, analytical standard

Synonym(s):

O,O-Dimethyl O-(4-nitrophenyl) phosphorothioate, Methyl parathion

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About This Item

Empirical Formula (Hill Notation):
C8H10NO5PS
CAS Number:
298-00-0
Molecular Weight:
263.21
Beilstein:
8905814
EC Number:
206-050-1
MDL number:
MFCD00041813
UNSPSC Code:
12000000
PubChem Substance ID:
24872575

grade

analytical standard

product line

PESTANAL®

CofA

current certificate can be downloaded

packaging

ampule of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

room temp

SMILES string

COP(=S)(OC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChI key

RLBIQVVOMOPOHC-UHFFFAOYSA-N

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General description

Parathion-methyl is an organophosphate insecticide, which is extensively used for agricultural purposes. Its mode of action involves the inactivation of the enzyme acetylcholinesterase (AChE) in insects and also mammals. It undergoes degradation by soil microorganisms to yield p-nitrophenol as the product.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 3 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

114.8 °F - open cup

Flash Point(C)

46 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
LRAB8147
LC24640V
LC22545V
LC16218V
LC12144V

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Effect of paraoxon-methyl and parathion-methyl on DNA in human lymphocytes and protective action of vitamin C
Blasiak J and Kowalik J
Pest Management Science, 55(12), 1182-1186 (1999)
Isolation, characterization and identification of methyl parathion degrading bacteria from industrial waste
Vadukia, et al.
Journal of Cell and Tissue Research, 14(3), 4633-4633 (2014)
Absorption, distribution, metabolism and excretion of daily oral doses of [14 C] methyl parathion in hens
Abu-Qare WA, et al.
Toxicology Letters, 125(1), 1-10 (2001)
Mohamed Abdel-Razek Saleh Abdel-Razek et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(6), 449-461 (2013-03-05)
The goal of this study was to optimize methyl parathion (O,O-dimethyl-O-4-p-nitrophenyl phosphorothioate) degradation using a strain of Escherichia coli DH5α expressing the opd gene. Our results indicate that this strain had lower enzymatic activity compared to the Flavobacterium sp. ATCC
Scott A Trammell et al.
Chemical communications (Cambridge, England), 48(34), 4121-4123 (2012-03-22)
Using a low power green laser, we have demonstrated a rate acceleration of ~2-fold for the hydrolysis of methyl parathion by irradiating the plasmon absorption band of Au nanoparticles capped with a Cu(bpy) catalyst.
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