SML3863

Tecovirimat

≥98% (HPLC)

• Synonym(s): 4-Trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide, SIGA-246, ST-246, rel-N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)benzamide
• Empirical Formula (Hill Notation): C₁₉H₁₅F₃N₂O₃
• CAS Number: 869572-92-9
• Molecular Weight: 376.33
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Description

Biochem/physiol Actions

Tecovirimat (ST-246) is an antiviral with activity against orthopoxviruses such as cowpox and monkeypox and including smallpox. Tecovirimat inhibits the function of a major envelope protein required for the production of extracellar virus, prevented the virus from leaving the cell, and spreading within the body. FDA-approved for the treatment of human smallpox disease caused by Variola virus in adults and children.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable