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Key Documents

SML3394

Sigma-Aldrich

GZ-11608

≥98% (HPLC)

Synonym(s):

4-​Methoxy-​N-​[(1S)​-​1-​methyl-​2-​phenylethyl]​-benzenepropanamine, S-3-(4-Methoxyphenyl)-N-(1-phenylpropan-2-yl)propan-1-amine

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About This Item

Empirical Formula (Hill Notation):
C19H25NO
CAS Number:
Molecular Weight:
283.41
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

Assay

≥98% (HPLC)

form

oil

color

colorless to brown

storage temp.

2-8°C

Biochem/physiol Actions

GZ-11608 is a potent and selective inhibitor of vesicular monoamine transporter-2 (VMAT2) that diminished hERG interaction. GZ-11608 reduces behavioral effects of methamphetamine such as locomotor activity, self-administration, and methamphetamine seeking behavior. It does not exhibit abuse liability. GZ-11608 inhibits methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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