SAB3500768
Anti-TLR8 antibody produced in rabbit
affinity isolated antibody
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About This Item
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biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
mol wt
115 kDa
species reactivity
human
concentration
1 mg/mL
technique(s)
ELISA: suitable
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TLR8(51311)
Immunogen
Antibody was raised against a 13 amino acid peptide near the amino terminus of human TLR8.
Features and Benefits
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Linkage
The action of this antibody can be blocked using blocking peptide SBP3500768.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
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Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Journal of immunology (Baltimore, Md. : 1950), 193(10), 5118-5128 (2014-10-10)
Nucleic acid-sensing TLRs are involved in both antimicrobial immune responses and autoimmune inflammation. TLR8 is phylogenetically and structurally related to TLR7 and TLR9, which undergo proteolytic processing in the endolysosomes to generate functional receptors. Recent structural analyses of human TLR8
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