PKH67GL
PKH67 Green Fluorescent Cell Linker Kit for General Cell Membrane Labeling
Distributed for Phanos Technologies
Synonym(s):
Green PKH membrane labeling kit
About This Item
Recommended Products
Quality Level
packaging
pkg of 1 kit
storage condition
protect from light
fluorescence
λex 490 nm; λem 502 nm (PKH67 dye)
detection method
fluorometric
shipped in
ambient
storage temp.
room temp
Application
- To label and further investigate the exosomes expelled from cells in triple-negative breast cancer condition.
- To label apoptotic cells, in order to study the role of ανβ5 receptor in both binding and internalization of apoptotic cells.
- In fluorescence imaging.
Slow loss of fluorescence has been observed in in vivo studies using PKH1 and PKH2. PKH67 may exhibit similar properties since this behavior appears to be characteristic of green cell linker dyes, but not red cell linker dyes. Correlation of in vitro cell membrane retention with in vivo fluorescence half life in non-dividing cells predicts an in vivo fluorescence half life of 10-12 days for PKH67. Other green cell linker dyes with similar half lives have been used to monitor in vivo lymphocyte and macrophage trafficking over periods of 1-2 months, suggesting that PKH67 will also be useful for in vivo tracking studies of moderate length.
Linkage
Legal Information
Kit Components Only
- Diluent C 6 x 10
- PKH67 Cell Linker in ethanol .5 mL
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
Flash Point(F)
57.2 °F - closed cup
Flash Point(C)
14 °C - closed cup
Certificates of Analysis (COA)
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