O1882
N-Octanoyl-D-sphingosine
waxy solid
Synonym(s):
C8 ceramide
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About This Item
Empirical Formula (Hill Notation):
C26H51NO3
Molecular Weight:
425.69
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
form
waxy solid
solubility
DMSO or ethanol: soluble
shipped in
wet ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
InChI key
APDLCSPGWPLYEQ-WRBRXSDHSA-N
Biochem/physiol Actions
Synthetic anaolgue of natural ceramide, activates protein kinase C, stimulates IL-2 production and induces apoptosis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Katsushige Hattori et al.
Endocrinology, 159(6), 2337-2347 (2018-04-19)
LH supplementation in assisted reproductive technology cycles improves the ongoing pregnancy rate in women with poor ovarian response (POR). However, our knowledge of the precise role of LH during the follicular phase of the menstrual cycle is incomplete. To explore
Albert Koulman et al.
Rapid communications in mass spectrometry : RCM, 23(10), 1411-1418 (2009-04-07)
Most analytical methods in metabolomics are based on one of two strategies. The first strategy is aimed at specifically analysing a limited number of known metabolites or compound classes. Alternatively, an unbiased approach can be used for profiling as many
W D Jarvis et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(1), 73-77 (1994-01-04)
The potential involvement of ceramide-related signaling processes in the induction of apoptosis by tumor necrosis factor alpha was assessed by multiple biochemical strategies in the human leukemic cell lines HL-60 and U937 and the murine fibrosarcoma cell lines L929/LM and
Giuseppe Astarita et al.
PloS one, 10(2), e0116961-e0116961 (2015-02-12)
Methamphetamine is a highly addictive psychostimulant that causes profound damage to the brain and other body organs. Post mortem studies of human tissues have linked the use of this drug to diseases associated with aging, such as coronary atherosclerosis and
Curtis J Pritzl et al.
Journal of immunology (Baltimore, Md. : 1950), 194(9), 4339-4349 (2015-03-27)
The ceramide family of lipids plays important roles in both cell structure and signaling in a diverse array of cell types, including immune cells. However, very little is known regarding how ceramide affects the activation of dendritic cells (DCs) in
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