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Key Documents

MBD0009

Sigma-Aldrich

Inactivated Porphyromonas gingivalis

Suitable for DNA extraction, PCR, sequencing, next generation sequencing, >10^8 bacteria/vial

Synonym(s):

Standard DNA

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About This Item

UNSPSC Code:
41105500
NACRES:
NA.51

Quality Level

200

form

powder

concentration

>10^8 bacteria/vial

technique(s)

DNA extraction: suitable
DNA sequencing: suitable
PCR: suitable

shipped in

dry ice

storage temp.

−20°C

General description

Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses. Inactivated Prophyromonas gingivalis can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs. Porphyromonas gingivalis, is a gram negative bacterium which is an etiologic agent of adult periodontitis, a chronic inflammatory disease characterized by the destruction of the supportive tissue surrounding teeth. Studies have shown that LPS from P. gingivalis plays an important role in this disease. The association of the oral microbiota, including P. gingivalis, with various pathological states has been reported. These include development of Alzheimer’s disease, role in oral cancers, preterm birth and rheumatoid arthritis.

Read here how to use our standards to ensure data integrity for your microbiome research.

Application

Inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder. It is recommended to avoid freeze thaw cycles of this product.

Physical form

Powder -The inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

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Articles

DNA Standards for Metagenomic Research into Microbiome Communities

The use of standards is critical to the integrity of metagenomics research. Learn how DNA standards for bacteria, fungi, and viruses are applied to studying the microbiome. Choose standards for E. coli and other key species, as well as mixed community standards.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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