M104

(±)-Muscarine chloride hydrate

≥98% (HPLC)

• Synonym(s): Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate
• Empirical Formula (Hill Notation): C₉H₂₀ClNO₂ · xH₂O
• CAS Number: 2936-25-6
• Molecular Weight: 209.71 (anhydrous basis)
• MDL number: MFCD00055067
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278578
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: deionized water: ≥20 mg/mL
• storage temp.: room temp
• SMILES string: [Cl-].CC1OC(CC1O)C[N+](C)(C)C
• InChI: 1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1
• InChI key: WUFRNEJYZWHXLC-UHFFFAOYSA-M
• Gene Information: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

Description

Application

(±)-Muscarine chloride hydrate may be used:

• as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
• as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
• as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves