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G5630

Sigma-Aldrich

Gly-Gly-Gly-Gly-Gly-Gly

Synonym(s):

Hexaglycine

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About This Item

Empirical Formula (Hill Notation):
C12H20N6O7
CAS Number:
3887-13-6
Molecular Weight:
360.32
MDL number:
MFCD00083697
UNSPSC Code:
12352200
PubChem Substance ID:
24895220
NACRES:
NA.26

form

solid

Quality Level

200

color

white

mp

314.5 °C

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C12H20N6O7/c13-1-7(19)14-2-8(20)15-3-9(21)16-4-10(22)17-5-11(23)18-6-12(24)25/h1-6,13H2,(H,14,19)(H,15,20)(H,16,21)(H,17,22)(H,18,23)(H,24,25)

InChI key

XJFPXLWGZWAWRQ-UHFFFAOYSA-N

Related Categories

Application

Hexaglycine and capped hexaglycine are used in physicochemical studies of peptide structure dynamics. Hexaglycine is used as a model compound in development of peptide quantitation and separation methods.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lys-Lys-Lys-Lys ≥95% (TLC)

Sigma-Aldrich

L9026

Lys-Lys-Lys-Lys

Triglycine United States Pharmacopeia (USP) Reference Standard

USP

1686386

Triglycine

Leu-Leu-Leu ≥90% (elemental analysis)

Sigma-Aldrich

L0879

Leu-Leu-Leu

Voislav Blagojevic et al.
The Analyst, 135(6), 1456-1460 (2010-05-26)
A novel method is presented for the quantitation of peptides based on their methylation by in vacuo chemical reaction with methyl iodide. Samples of two small peptides, hexaglycine and pentaalanine, were labeled with CH(3)I and CD(3)I, representing the "unknown" and
Joshua A Plumley et al.
The journal of physical chemistry. B, 115(6), 1562-1570 (2011-01-26)
We compare the energies and enthalpies of inter-action of three- and seven-stranded capped polyglycine aggregates in both the pleated and rippled antiparallel and parallel β-sheet structures as well as the collagenic (three-strand) or polyglycine II-like (seven-strand) forms using density functional
Punam Dalai et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 47(4), 427-452 (2016-10-21)
On the Hadean-Early Archean Earth, the first islands must have provided hot and dry environments for abiotically formed organic molecules. The heat sources, mainly volcanism and meteorite impacts, were also available on Mars during the Noachian period. In recent work
Brett Harper et al.
Journal of the American Society for Mass Spectrometry, 25(10), 1716-1729 (2014-07-30)
It is shown that y-type ions, after losing C-terminal H2O or NH3, can lose an internal backbone carbonyl (CO) from different peptide positions and yield structurally different product fragment ions upon collision-induced dissociation (CID). Such CO losses from internal peptide

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