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C2485

Sigma-Aldrich

β-Cyclodextrin polymer

powder

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About This Item

MDL number:
MFCD03456204
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

synthetic

Quality Level

100

form

powder

mol wt

average mol wt 2,000-300,000 Da

composition

Cyclodextrin content, 60% iodometric

color

white

solubility

H2O: soluble 100mg plus 1 mL, clear, colorless to light yellow

storage temp.

2-8°C

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General description

Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1,4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivatized through esterification at positions two, three and/or six.

Application

Beta-cyclodextrin (β-Cyclodextrin) may be used in the development of biocompatible drug delivery vehicles and membrane constructs to improve compound solubility in aqueous environments. β-cyclodextrin polymer and its ester derivatives are used for the development and construction of biomaterials such as hydrogels, nanoassemblies and biomatricies. β-cyclodextrin may be used for the development of biosensors.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jun Zhao et al.
Journal of chromatography. A, 1216(45), 7840-7845 (2009-10-10)
The expansion and hydrodynamic properties of matrix are significant for expanded bed adsorption (EBA) processes. A series of new composite matrices CroCD-TuC are studied and estimated in an expanded bed. It is found that the heavier matrix is better suited
S Daoud-Mahammed et al.
Journal of biomedical materials research. Part A, 86(3), 736-748 (2007-11-29)
This study aims to investigate the rheological properties of self-assembling gels containing cyclodextrins with potential application as injectable matrix for the sustained delivery of poorly soluble drugs. The ability of these gels to entrap two hydrophobic molecules, benzophenone (BZ) and
Jie Li et al.
Fitoterapia, 93, 163-167 (2014-01-22)
Six 3,3″-biflavanones, including a new compound isochamaejasmenin C (1), were isolated from EtOH extracts of the roots of Stellera chamaejasme L. Their structures were elucidated on the basis of spectroscopic methods, including HR-ESI-MS and 2D NMR techniques. The absolute configurations
Thimma Reddy Thatiparti et al.
Macromolecular bioscience, 10(1), 82-90 (2009-09-10)
Novel beta-cyclodextrin polymer (CD)-based drug delivery hydrogels were prepared by varying type and concentration of crosslinkers and optimizing the gel synthesis conditions. For comparison, dextrose gels were prepared using the same crosslinkers. The optimized gels were characterized by Fourier Transform
Chao Yuan et al.
Food chemistry, 152, 140-145 (2014-01-22)
The inclusion complex of ethyl benzoate with hydroxypropyl-β-cyclodextrin (HPCD) was prepared by a freeze-drying method and its characterizations were investigated by different analytical techniques including UV, FT-IR and phase solubility methods. All these approaches indicated that ethyl benzoate was able
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Articles

Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nanoparticles

Dmitri Simberg (University of Colorado Anschutz Medical Campus, USA) reviews the used of dextran and cyclodextrin for the synthesis of nanoparticles used in drug delivery applications.

Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nanoparticles

Dmitri Simberg (University of Colorado Anschutz Medical Campus, USA) reviews the used of dextran and cyclodextrin for the synthesis of nanoparticles used in drug delivery applications.

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