Skip to Content
Merck
All Photos(1)

Key Documents

43623

Supelco

β-Sitosterol

analytical standard

Synonym(s):

α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C29H50O
CAS Number:
Molecular Weight:
414.71
Beilstein:
1916165
EC Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥90.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤10.0% water

mp

136-140 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC

InChI

1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key

KZJWDPNRJALLNS-VJSFXXLFSA-N

Looking for similar products? Visit Product Comparison Guide

General description

β-Sitosterol is an abundantly found phytosterol in plants. It is known to show anti-inflammatory, immune-modulating, antipyretic, antineoplastic, and blood sugar-controlling properties. β-Sitosterol also acts as an estrogen and estrogen receptor (ERα and Erβ) agonist.

Application

This analytical standard can also be used as follows:
  • Identification and determination of β-sitosterol and stigmasterol in the hydro-alcohol extract, prepared from the leaves of B. bambo by reversed-phase high-performance liquid chromatography (RP-HPLC) coupled to photo-diode array detector (PDA)
  • Development and validation of two high-performance thin layer chromatography (HPTLC) methods to quantify four biomarkers— β-sitosterol, β-amyrin, lupeol, and ursolic acid in the ethanol extract of G. senegalensis leaves
  • Secondary metabolite profiling of various plant parts collected from 82 plants belonging to 21 different cannabis strains using gas chromatography-mass spectrometry (GC-MS) for sterols and terpenoids (mono-, sesqui-, tri-), and high-performance liquid chromatography (HPLC) with UV and mass spectrometric (MS) detection for flavonoids
  • High-performance thin layer chromatographic (HPTLC) method-based quantification of β-sitosterol in a herbal formulation prepared from the roots of Gmelina arborea using silica gel precoated 60 F254 aluminum plates
  • Determination of free sterols or oxysterols in food matrices, using gas chromatography and ion trap mass spectrometry (GC-MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

?-Sitosterol activates Fas signaling in human breast cancer cells
Awad.B.A, et al.
Phytomedicine, 14, 747-754 (2007)
New method to determine free sterols/oxysterols in food matrices using gas chromatography and ion trap mass spectrometry (GC?IT-MS)
Szterk A and Pakula L
Talanta, 152, 54-75 (2016)
Günther Silbernagel et al.
Current opinion in lipidology, 24(1), 12-17 (2012-11-21)
Plant sterols as ingredients to functional foods are recommended for lowering LDL cholesterol. However, there is an ongoing discussion whether the use of plant sterols is safe. Genetic analyses showed that common variants of the ATP binding cassette transporter G8
Katarzyna Hąc-Wydro
Colloids and surfaces. B, Biointerfaces, 110, 113-119 (2013-05-29)
In this paper the influence of one of phytosterols, namely β-sitosterol on cholesterol (Chol)/phosphatidylcholine (PC)/ganglioside (GM3) monolayers was examined to find the correlation between the properties of model system and the effect of phytocompound. The studied monolayers differed in condensation
Ikarastika Rahayu Abdul-Wahab et al.
Journal of ethnopharmacology, 144(3), 741-746 (2012-10-27)
Local communities in Malaysia consume Pereskia bleo Kunth. (Cactaceae) leaves as raw vegetables or as a concoction and drink as a tea to treat diabetes, hypertension, rheumatism, cancer-related diseases, inflammation, gastric pain, ulcers, and for revitalizing the body. To evaluate

Protocols

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service