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W323500

Sigma-Aldrich

4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran

≥95%

Synonym(s):

Menthofuran

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About This Item

Empirical Formula (Hill Notation):
C10H14O
CAS Number:
494-90-6
Molecular Weight:
150.22
FEMA Number:
3235
EC Number:
207-795-5
Council of Europe no.:
2265
MDL number:
MFCD00041851
UNSPSC Code:
12164502
PubChem Substance ID:
24901573
Flavis number:
13.035
NACRES:
NA.21

biological source

synthetic

grade

Halal

reg. compliance

FDA 21 CFR 117

Assay

≥95%

optical activity

[α]25/D +90°, c = 10 in methanol

refractive index

n20/D 1.485 (lit.)

bp

80-82 °C/13 mmHg (lit.)

density

0.97 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

coffee; musty; earthy; pungent; nutty

storage temp.

2-8°C

SMILES string

CC1CCc2c(C)coc2C1

InChI

1S/C10H14O/c1-7-3-4-9-8(2)6-11-10(9)5-7/h6-7H,3-5H2,1-2H3

InChI key

YGWKXXYGDYYFJU-UHFFFAOYSA-N

General description

4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran, a monoterpene flavor compound, is one of the key constituents of peppermint oil and Euodia hortensis forma hortensis leaf oil.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

168.8 °F - closed cup

Flash Point(C)

76 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN3468
SHBL5129
MKCJ4005
MKCH3916
MKCB3560

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Kazuki Togashi et al.
Scientific reports, 9(1), 1704-1704 (2019-02-10)
Mint plants could theoretically serve as companion plants (CPs) that attract enemies of herbivores in tritrophic interactions. In order to explore the traits of mint volatiles as attractant cues for enemies of two-spotted spider mites, we performed Y-tube olfactometer assays
Flavor chemistry of peppermint oil (Mentha piperita L.).
Guntert M, et al.
ACS Symp. Ser., 794, 119?137-119?137 (2001)
The volatile oils of Euodia hortensis forma hortensis.
Brophy JJ, et al.
Flavour and Fragrance Journal, 1(1), 17-20 (1985)
Valerie M Kramlinger et al.
Chemico-biological interactions, 197(2-3), 87-92 (2012-04-11)
Nicotine is the primary addictive agent in tobacco products and is metabolized in humans by CYP2A6. Decreased CYP2A6 activity has been associated with decreased smoking. The extrahepatic enzyme, CYP2A13 (94% identical to CYP2A6) also catalyzes the metabolism of nicotine, but
S C Khojasteh-Bakht et al.
Drug metabolism and disposition: the biological fate of chemicals, 26(7), 701-704 (1998-07-14)
(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 (CYP or P450) 2A6. Menthofuran caused a time- and concentration-dependent loss of CYP2A6 activity. The inactivation of CYP2A6 was characterized by a Ki of 2.5 microM and a kinact
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Protocols

GC Analysis of Peppermint Essential Oil on SLB®-IL59

Cymene; 4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran; Linalool; Menthol; Menthone; Menthyl acetate; Germacrene D; Bicyclogermacrene; Thymol

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