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JKA10019

Sigma-Aldrich

8arm-PEG20K

average MN 20,000, Maleimide, tripentaerythritol core, thiol reactive

Synonym(s):

8arm-PEG-Maleimide, Polyethylene glycol

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About This Item

Linear Formula:
R(O(CH2CH2O)nCH2CH2NHCOCH2CH2C4H2O2N)8
UNSPSC Code:
12162002
NACRES:
NA.23

product name

8arm-PEG20K-Maleimide, tripentaerythritol core, average Mn 20,000

form

solid

mol wt

average Mn 20,000

reaction suitability

reactivity: thiol reactive

polymer architecture

shape: 8-arm
functionality: homofunctional

storage temp.

−20°C

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General description

8arm PEG Maleimide. Crosslinks into hydrogels. MAL is selective for thiol groups on cystein side chains; reacts at pH 5.0-6.5. 8ARM(TP)-PEG with tripentaerythritol core has a lower polydispersity and higher molecular weight accuracy compared with the generic 8ARM-PEG with a hexaglycerin core.

Application

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Articles

Applications of Y-Shape Peg Derivatives for Drug Delivery

The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids are hydrolyzed by nucleases; and most small molecules are eliminated in the liver and kidneys.

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