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Key Documents

91415

Sigma-Aldrich

(Triisopropylsiloxy)methyl chloride

≥95.0% (GC)

Synonym(s):

(Chloromethoxy)triisopropylsilane, TOMCl

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About This Item

Empirical Formula (Hill Notation):
C10H23ClOSi
CAS Number:
Molecular Weight:
222.83
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

Assay

≥95.0% (GC)

form

liquid

density

0.96 g/mL at 20 °C (lit.)

SMILES string

CC(C)[Si](OCCl)(C(C)C)C(C)C

InChI

1S/C10H23ClOSi/c1-8(2)13(9(3)4,10(5)6)12-7-11/h8-10H,7H2,1-6H3

InChI key

SYZFQLUYDBIQCR-UHFFFAOYSA-N

Other Notes

Fluoride-labile 2′-O-protecting group for RNA oligonucleotide synthesis

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S. Pitsch et al.
Helvetica Chimica Acta, 82, 1753-1753 (1999)
S. Eppacher et al.
Helvetica Chimica Acta, 87, 3004-3004 (2004)
S. Pitsch et al.
Helvetica Chimica Acta, 84, 3773-3773 (2001)

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