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719854

Sigma-Aldrich

Resomer® L 206 S, Poly(L-lactide), ester terminated

Synonym(s):

PLL

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About This Item

Empirical Formula (Hill Notation):
CH3O(C6H8O4)nH
UNSPSC Code:
12162002
NACRES:
NA.23

form

granular

degradation timeframe

>3 years

viscosity

0.8-1.2 dL/g, 0.1 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tm 180-185 °C
Tg 60-65 °C

storage temp.

2-8°C

General description

Resomer® L 206 S, Poly(L-lactide) (PLLA) is a high-performance biodegradable polymer with an ester-terminated end group. Its properties include good mechanical stability, hydrophobicity, and excellent composting characteristics. It is a non-toxic, biocompatible, and bioresorbable polymer widely used in biomedical applications.

Application

Resomer® L 206 S, Poly(L-lactide) (PLLA) is an optically active and semi-crystalline material that can be used in the fabrication of biomedical devices and research tissue engineering solutions, such as orthopedics, soft tissue fixation devices, sports medicine, plates, screws, nails, and stents. This bioresorbable material exhibits a resorption period greater than 3 years whereas the inherent viscosity is 0.8–1.2. The advancement in biomedical applications such as osteoconductivity of these composite materials has improved by the introduction of calcium-based inorganic additives.

Legal Information

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Synthesis and properties of Poly (L-lactide)-Poly (ε-caprolactone) multiblock copolymers by the self-polycondensation of diblock macromonomers
J Mitsutoshi, et al.
Polymer Journal, 47(10), 657-665 (2015)

Articles

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

Related Content

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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