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123056

Sigma-Aldrich

4-(2-Aminoethyl)aniline

97%

Synonym(s):

4-Aminophenethylamine

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About This Item

Linear Formula:
H2NC6H4CH2CH2NH2
CAS Number:
Molecular Weight:
136.19
Beilstein:
1099913
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

refractive index

n20/D 1.591 (lit.)

bp

103 °C/0.3 mmHg (lit.)

mp

28-31 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

NCCc1ccc(N)cc1

InChI

1S/C8H12N2/c9-6-5-7-1-3-8(10)4-2-7/h1-4H,5-6,9-10H2

InChI key

LNPMZQXEPNWCMG-UHFFFAOYSA-N

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General description

4-(2-Aminoethyl)aniline undergoes coupling with carbohydrates by reductive amination to yield modified carbohydrates.

Application

4-(2-Aminoethyl)aniline has been used in chemical modification of silk fibroin to tailor the overall hydrophilicity and structure of silk. It has been used as reagent in polycondensation reactions.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mihaela Badea et al.
Biosensors & bioelectronics, 18(5-6), 689-698 (2003-04-23)
Glucose oxidase, lactate oxidase, L-aminoacid oxidase and alcohol oxidase were immobilised on new films based on 2,6-dihydroxynaphthalene (2,6-DHN) copolymerised with 2-(4-aminophenyl)-ethylamine (AP-EA) onto the Pt electrodes. The electropolymerisation was performed by cyclic voltammetry. Different scan rates and scan potential ranges
Mitsuo Okada et al.
Plant & cell physiology, 43(5), 505-512 (2002-06-01)
Binding experiments as well as affinity labeling with an (125)I-labeled 2-(4-aminophenyl)ethylamino derivative of N-acetylchitooctaose revealed the presence of high-affinity binding sites/proteins for N-acetylchitooligosaccharide elicitor in the plasma membrane preparation from suspension-cultured carrot cells, barley cells and wheat leaves. Their binding
Chem. Abstr., 116, 106932j-106932j (1992)
H D Grimmecke et al.
Glycoconjugate journal, 15(6), 555-562 (1999-01-09)
Reductive amination of 3-deoxy-D-manno-octulosonic acid (Kdo) with allylamine (AIIN) or 2-(4-aminophenyl)ethylamine (APEA) yields epimer pairs of 2-N-allylamino and 2-N-[2-(4-aminophenyl)ethylamino]-2,3-dideoxy-D-glycero-D-galacto- and -2,3-dideoxy-D-glycero-D-talo-octonic acid. The yields were 50-60% due to reduction of Kdo to the respective polyols as side reaction products. Mass
An improved method for the preparation of derivatives of reducing oligosaccharide with 2-(4-aminophenyl)ethylamine.
L H Semprevivo
Carbohydrate research, 177, 222-227 (1988-06-15)

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