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1625009

USP

Sulfadiazine

Name: Sulfadiazine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N¹-(Pyrimidin-2-yl)sulfanilamide

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About This Item

Formule empirique (notation de Hill):

C₁₀H₁₀N₄O₂S

Numéro CAS:

68-35-9

Poids moléculaire :

250.28

Numéro Beilstein :

6733588

Numéro MDL:

MFCD00006065

Code UNSPSC :

41116107

ID de substance PubChem :

329751168

Nomenclature NACRES :

NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sulfadiazine

Fabricant/nom de marque

USP

Pf

253 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES

Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

InChI

1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

Clé InChI

SEEPANYCNGTZFQ-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sulfadiazine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Silver Sulfadiazine Cream
Sulfadiazine
Sulfadiazine Sodium
Sulfadiazine Tablets

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Warning

Mentions de danger

H302,H361d,H411

Conseils de prudence

P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome.

K Becker et al.

Medicine, 75(4), 185-194 (1996-07-01)

We performed a computerized search on sulfadiazine-associated nephrotoxicity reported in human immunodefiency virus (HIV)-infected patients in the international literature. Including an original case report, we summarized 35 acquired immunodefiency syndrome (AIDS) patients from 1987 to 1995 in an analysis comparing

[Acute kidney failure caused by sulfadiazine stones. A complication of the therapy of toxoplasmosis in AIDS].

U Kronawitter et al.

Deutsche medizinische Wochenschrift (1946), 118(46), 1683-1686 (1993-11-19)

A 45-year-old man with AIDS was treated for a recurrence of cerebral toxoplasmosis with sulphadiazine, 4 g, and pyrimethamine, 75 mg, daily. Owing to a lack of appetite and dysphagia he drank rather little water during the first week of

Sulfadiazine-induced nephrolithiasis in children.

Charlotte Catalano-Pons et al.

Pediatric nephrology (Berlin, Germany), 19(8), 928-931 (2004-06-19)

Sulfadiazine-associated urinary calculi have been described in HIV-positive adult patients but rarely in children. We report two pediatric cases of sulfadiazine-induced nephrolithiasis and review 45 adult cases from the literature. One had a hyper-IgM syndrome and was treated with sulfadiazine

Sulfadiazine crystalluria revisited. The treatment of Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome.

D I Simon et al.

Archives of internal medicine, 150(11), 2379-2384 (1990-11-01)

Toxoplasma gondii encephalitis is an important opportunistic infection in the acquired immunodeficiency syndrome, estimated to occur in 20,000 to 40,000 patients with acquired immunodeficiency syndrome in the United States by 1991. The combination of sulfadiazine and pyrimethamine is regarded as

Silver sulfadiazine: an antibacterial agent for topical use in burns. A review of the literature.

S Hoffmann

Scandinavian journal of plastic and reconstructive surgery, 18(1), 119-126 (1984-01-01)

Topical antibacterial treatment is of major importance in the burn patient. Silver sulfadiazine is an effective agent with low toxicity and few side effects. Deposition of silver in tissues, and absorption of sulfadiazine are both minimal. Present and future problems

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