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1366002

USP

Lidocaine

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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About This Item

Formule empirique (notation de Hill):
C14H22N2O
Numéro CAS:
137-58-6
Poids moléculaire :
234.34
Numéro MDL:
MFCD00026733
Code UNSPSC :
41116107
ID de substance PubChem :
329750054
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

lidocaine

Fabricant/nom de marque

USP

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

Clé InChI

NNJVILVZKWQKPM-UHFFFAOYSA-N

Informations sur le gène

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lidocaine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay, identification and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Lidocaine
  • Lidocaine Hydrochloride Topical Solution
  • Lidocaine Hydrochloride Oral Topical Solution
  • Lidocaine Hydrochloride Jelly

Actions biochimiques/physiologiques

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

L0595000

Lidocaine, European Pharmacopoeia (EP) Reference Standard

L0600000

Lidocaine hydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1257

Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1669

2,6-Dimethylaniline, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1671

Lidocaine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1673

Lidocaine Related Compound H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1670

Lidocaine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1672

Lidocaine Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1674

Lidocaine Related Compound I, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1675

Lidocaine Related Compound J, Pharmaceutical Secondary Standard; Certified Reference Material

1366080

Lidocaine Related Compound H, United States Pharmacopeia (USP) Reference Standard

1366013

Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP727

Lidocaine, British Pharmacopoeia (BP) Reference Standard

BP214

Lidocaine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1995

Lidocaine Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1994

Lidocaine Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Lidocaine Hydrochloride Oral Topical Solution
United States Pharmacopeia, 44(4), 2626-2626 (2020)
Lidocaine Hydrochloride Jelly
United States Pharmacopeia, 43(6), 2625-2625 (2020)
Daniela Casoni et al.
Veterinary anaesthesia and analgesia, 42(3), 250-259 (2014-07-22)
To determine the potency ratio between S-ketamine and racemic ketamine as inductive agents for achieving tracheal intubation in dogs. Prospective, randomized, 'blinded', clinical trial conducted in two consecutive phases. 112 client-owned dogs (ASA I or II). All animals were premedicated
Bartholomeus C M Benno Haarman et al.
Brain, behavior, and immunity, 40, 219-225 (2014-04-08)
The "monocyte-T-cell theory of mood disorders" regards neuroinflammation, i.e. marked activation of microglia, as a driving force in bipolar disorder. Microglia activation can be visualized in vivo using [(11)C]-(R)-PK11195 PET. Indirect evidence suggests the hippocampus as a potential focus of
Song-Young Park et al.
American journal of physiology. Heart and circulatory physiology, 307(3), H346-H352 (2014-06-08)
Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles.
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Articles

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

HILIC mobile phases consist of a high composition of acetonitrile, which facilitates the direct analysis of precipitated plasma samples without the need for additional sample solvent exchange.

LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

The benefit of HILIC over traditional reversed-phase chromatography is two-fold for both sample introduction and analyte detection. First, the high acetonitrile concentration of HILIC mobile phases allows for direct analysis of precipitated plasma samples without the need for additional sample solvent exchange. Second, the high acetonitrile content provides increased analyte response in positive ESI MS detection.

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