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1286005

USP

Folic acid

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

PteGlu, Pteroyl-L-glutamic acid, Vitamin M

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About This Item

Formule empirique (notation de Hill):
C19H19N7O6
Numéro CAS:
59-30-3
Poids moléculaire :
441.40
Beilstein:
100781
Numéro MDL:
MFCD00079305
Code UNSPSC :
41116107
ID de substance PubChem :
329749907
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

folic acid

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

Clé InChI

OVBPIULPVIDEAO-LBPRGKRZSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Folic acid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Folic Acid Tablets
  • Folic Acid Injection
  • Folic Acid Compounded Oral Solution
  • Oil- and Water-Soluble Vitamins with Minerals Chewable Gels
  • Leucovorin Calcium
  • Calcium l-5-Methyltetrahydrofolate Tablets

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

F0300000

Folic acid, European Pharmacopoeia (EP) Reference Standard

Y0001242

Folic acid impurity A, European Pharmacopoeia (EP) Reference Standard

Y0001243

Folic acid impurity D, European Pharmacopoeia (EP) Reference Standard

C0250000

Calcium folinate, European Pharmacopoeia (EP) Reference Standard

PHR1334

Folic Acid Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

1286027

Folic Acid Related Compound A, United States Pharmacopeia (USP) Reference Standard

1286300

10-Formylfolic acid, United States Pharmacopeia (USP) Reference Standard

1019870

4-Aminobenzoylglutamic acid, United States Pharmacopeia (USP) Reference Standard

BP937

Folic acid, British Pharmacopoeia (BP) Reference Standard

PHR2002

Folic Acid Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001979

Folic acid for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001980

Folic acid for impurity I identification, European Pharmacopoeia (EP) Reference Standard

PHR2001

Folic Acid Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002071

Calcium folinate for system suitability, European Pharmacopoeia (EP) Reference Standard

PHR2003

Folic Acid Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2334

10-Formylfolic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Krista S Crider et al.
The American journal of clinical nutrition, 98(5), 1272-1281 (2013-09-06)
Childhood asthma has become a critical public health problem because of its high morbidity and increasing prevalence. The impact of nutrition and other exposures during pregnancy on long-term health and development of children has been of increasing interest. We performed
Anja Osterhues et al.
Critical reviews in food science and nutrition, 53(11), 1180-1190 (2013-09-07)
The worldwide prevalence of neural tube defects (NTDs) has fallen noticeably during the past 30 years, but the specific etiology and causative mechanism of NTDs remain unknown. Since introduction of mandatory fortification of grains with folic acid, a further decrease in
Zohra S Lassi et al.
The Cochrane database of systematic reviews, 3(3), CD006896-CD006896 (2013-04-02)
During pregnancy, fetal growth causes an increase in the total number of rapidly dividing cells, which leads to increased requirements for folate. Inadequate folate intake leads to a decrease in serum folate concentration, resulting in a decrease in erythrocyte folate
Sreenivas P Veeranki et al.
American journal of epidemiology, 179(8), 938-946 (2014-03-29)
Viral bronchiolitis affects 20%-30% of infants; because there is no known effective treatment, it is important to identify risk factors that contribute to its pathogenesis. Although adequate folate intake during the periconceptional period prevents neural tube defects, animal data suggest
Susanna Kariluoto et al.
International journal of food microbiology, 176, 38-48 (2014-02-25)
The objective was to study folate production of yeast strains, bacteria isolated from oat bran, and selected lactic acid bacteria as well as one propionibacterium in oat and barley based models. Simultaneously, we aimed at sustaining the stability of viscosity
Afficher tous les articles scientifiques apparentés

Articles

HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express C18

Pyridoxine hydrochloride, ≥98% (HPLC); Nicotinamide, ≥98.5% (HPLC); Thiamine hydrochloride, reagent grade, ≥99% (HPLC); Biotin, ≥99.0% (T); Folic acid, analytical standard; Cyanocobalamin (B12), analytical standard; Riboflavin (B2), analytical standard

Protocoles

HPLC Analysis of Vitamins, Water Soluble on Discovery® C18

Separation of Pyridoxine; Nicotinamide; Nicotinic acid; Folic acid; (−)-Riboflavin, meets USP testing specifications; L-Ascorbic acid

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