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Astec® CYCLOBOND I 2000 HP-RSP Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

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About This Item

Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52

product name

Astec® Cyclobond I 2000 HP-RSP Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Matériaux

stainless steel column

Gamme de produits

Astec®

Conditionnement

pkg of 1 ea

Fabricant/nom de marque

Astec®

Paramètres

0-50 °C temperature
172 bar pressure (2500 psi)

Technique(s)

HPLC: suitable
LC/MS: suitable

L × D.I.

15 cm × 4.6 mm

Matrice

silica particle platform
fully porous particle

Groupe de la matrice active

cyclodextrin, beta- phase

Taille des particules

5 μm

Dimension de pores

100 Å

pH de fonctionnement

3.5-7

Technique de séparation

chiral

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Description générale

In the design of this new chemistry, it was an objective to create a very stable and reproducible phase with shorter retention times, while maintaining or improving selectivity over CYCLOBOND I 2000 RSP. With that goal and more achieved, CYCLOBOND I 2000 HP-RSP separates by extended H-bonding capability, and offers broad chiral selectivity for chiral screening. It is most beneficial for basic and neutral compounds.

  • Bonded phase: (R,S)-Hydroxypropyl modified β-cyclodextrin (high performance)

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Informations légales

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificats d'analyse (COA)

Lot/Batch Number
282128-01
282100-01
282070-01
278059-01
268604-01

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Consulter la Bibliothèque de documents

Assessment of the complexation degree of camptothecin derivatives and cyclodextrins using spectroscopic and separative methodologies
Foulon, C., et al.
Tetrahedron Asymmetry, 20 (21), 2482-2489 (2009)
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Weatherly, Choyce A., et al.
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
Roland Török et al.
Journal of chromatography. A, 1098(1-2), 75-81 (2005-11-30)
Direct high-performance liquid chromatographic methods were developed for the enantioseparation of (R,S)-bicalutamide (1) and its analogs (+/-)-3-chloro-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (2), (+/-)-N-(4-cyano-3-(trifluoro-methyl)phenyl)-2-methyloxirane-2-carboxamide (3), (+/-)-4-fluorophenylsulfonyl-2-hydroxy-2-methylpropionic acid (4) and (+/-)-3-hydroxy-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (5). The methods involved the use of a cellulose-based Chiralcel OD-H, macrocyclic glycopeptide-based Chirobiotic T
Xinxin Han et al.
Journal of chromatography. A, 1063(1-2), 111-120 (2005-02-11)
The enantiomeric separation of a set of 30 new chiral furan derivatives has been achieved on native and derivatized beta-cyclodextrin stationary phases using high performance liquid chromatography (HPLC). The hydroxypropyl-beta-cyclodextrin (Cyclobond RSP), the 2,3-dimethyl-beta-cyclodextrin (Cyclobond DM), and the acetyl-beta-cyclodextrin (Cyclobond

Contenu apparenté

Astec CYCLOBOND™

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

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