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Z4402

Sigma-Aldrich

Zinterol hydrochloride

≥98% (HPLC)

Synonyme(s) :

Zinterol hydrochloride, N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]-Methanesulfonamide Hydrochloride; MJ 9184

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About This Item

Formule empirique (notation de Hill):
C19H26N2O4S·HCl
Numéro CAS:
38241-28-0
Poids moléculaire :
414.95
Numéro MDL:
MFCD00867031
Code UNSPSC :
12352200
ID de substance PubChem :
329831614
Nomenclature NACRES :
NA.77

Pureté

≥98% (HPLC)

Forme

powder

Conditions de stockage

desiccated

Solubilité

DMSO: ≥15 mg/mL

Température de stockage

room temp

Chaîne SMILES 

CC(C)(Cc1ccccc1)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2

InChI

1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

Clé InChI

XJBCFFLVLOPYBV-UHFFFAOYSA-N

Actions biochimiques/physiologiques

Zinterol Hydrochloride is a β2 adrenergic receptor selective agonist.

Caractéristiques et avantages

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Consulter la Bibliothèque de documents

S Magne et al.
The Journal of biological chemistry, 276(43), 39539-39548 (2001-08-17)
We have recently reported that arachidonic acid mediates beta(2)-adrenergic receptor (AR) stimulation of [Ca(2+)](i) cycling and cell contraction in embryonic chick ventricular cardiomyocytes (Pavoine, C., Magne, S., Sauvadet, A., and Pecker, F. (1999) J. Biol. Chem. 274, 628-637). In the
Dana S Hutchinson et al.
Naunyn-Schmiedeberg's archives of pharmacology, 373(2), 158-168 (2006-04-08)
The present study investigates the action of zinterol at beta(3)-adrenoceptors. We used mouse primary brown adipocytes and Chinese hamster ovary (CHO-K1) cells expressing the mouse or human beta(3)-adrenoceptor. Zinterol was a full agonist at increasing cyclic AMP levels in primary
Su-Hyun Jo et al.
Circulation research, 91(1), 46-53 (2002-07-13)
Compartmentation of intracellular signaling pathways serves as an important mechanism conferring the specificity of G protein-coupled receptor (GPCR) signaling. In the heart, stimulation of beta2-adrenoceptor (beta2-AR), a prototypical GPCR, activates a tightly localized protein kinase A (PKA) signaling, which regulates
Sabine Bartel et al.
Cardiovascular research, 57(3), 694-703 (2003-03-06)
The role of cAMP in beta(2)-adrenoceptor signaling and its functional relevance in adult rat heart has been the subject of considerable controversy. Therefore, we investigated the beta(2)-adrenoceptor pathways in both adult cardiomyocytes and in the intact hearts of Wistar rats
Dana S Hutchinson et al.
Journal of neurochemistry, 103(3), 997-1008 (2007-08-08)
Isoprenaline, acting at beta-adrenoceptors (ARs), enhances memory formation in single trial discriminated avoidance learning in day-old chicks by mechanisms involving alterations in glucose and glycogen metabolism. Earlier studies of memory consolidation in chicks indicated that beta3-ARs enhanced memory by increasing
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β-Adrenoceptors

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