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T1875

Sigma-Aldrich

Testosterone propionate

solid

Synonyme(s) :

17β-hydroxy-4-androstène-3-one 17-propionate, 4-androstène même-17β-ol-3-one 17-propionate

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About This Item

Formule empirique (notation de Hill):
C22H32O3
Numéro CAS:
57-85-2
Poids moléculaire :
344.49
Numéro Beilstein :
3221760
Numéro CE :
200-351-1
Numéro MDL:
MFCD00003653
Code UNSPSC :
51111800
ID de substance PubChem :
24899994
Nomenclature NACRES :
NA.77

Source biologique

synthetic (organic)

Niveau de qualité

200

Stérilité

non-sterile

Pureté

≥98% (HPLC)

Forme

solid

Contrôle du médicament

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

Couleur

white

Solubilité

acetone: soluble 1 in 4 of acetone
chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
ethanol: soluble 1 in 6 of ethanol
ethyl oleate: soluble 1 in 20 of ethyl oleate
propylene glycol: soluble 1 in 30 of propylene glycol
soluble 1 in 20 of ethyl oleate
ethanol: 10 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL
H2O: insoluble
oil: soluble

Conditions d'expédition

ambient

Température de stockage

room temp

Chaîne SMILES 

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC

InChI

1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1

Clé InChI

PDMMFKSKQVNJMI-BLQWBTBKSA-N

Informations sur le gène

human ... AR(367) , CYP17A1(1586)
rat ... Ar(24208)

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Application

Testosterone propionate has been used for studying its effects on pregnant ewes,.

Actions biochimiques/physiologiques

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.

Forme physique

Photosensitive solid

Notes préparatoires

This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.

Pictogrammes

Health hazardExclamation markEnvironment
GHS08,GHS07,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302,H351,H360FD,H400

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificats d'analyse (COA)

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