SRP0114

NCOR2/SMRT human

recombinant, expressed in E. coli, ≥60% (SDS-PAGE)

• Synonyme(s) : Nuclear receptor corepressor 2, SMRTe, Silencing mediator of retinoic acid and thyroid hormone receptor, T3 receptor-associating factor, TRAC-1
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Produit recombinant: expressed in E. coli
• Pureté: ≥60% (SDS-PAGE)
• Forme: aqueous solution
• Poids mol.: 39 kDa
• Conditionnement: pkg of 50 μg
• Concentration: >0.02 mg/mL
• Numéro d'accès NCBI: NM_006312
• Numéro d'accès UniProt: Q9Y618
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... NCOR2(9612)

Description

Description générale

Human NCOR2/SMRT, DAD domain, amino acid 395-489, GenBank Accession No. NM_006312, N-terminal ST tag, MW = 39 kDa, expressed in E. coli system. NcoR2, nuclear receptor corepressor, are transcriptional corepressors.

Application

Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling.

Forme physique

Formulated in 50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 20 mM glutathione, and 10% glycerol.

Notes préparatoires

Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.