SML3797

Biotin-HPDP

≥95% (HPLC)

• Synonyme(s) : (3aS,4S,6aR)-Hexahydro-2-oxo-N-[6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]-1H-thieno[3,4-d]imidazole-4-pentanamide, HPDP-Biotin, N-[6-(Biotinamido)hexyl]-3′-(2′-pyridyldithio)propionamide
• Formule empirique (notation de Hill): C₂₄H₃₇N₅O₃S₃
• Numéro CAS: 129179-83-5
• Poids moléculaire : 539.78
• Numéro MDL: MFCD00078541
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Forme: powder
• Conditions de stockage: protect from light
• Couleur: white to beige
• Solubilité: DMSO: 2 mg/mL, clear (Warmed)
• Température de stockage: -10 to -25°C
• Chaîne SMILES: S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)NCCCCCCNC(=O)CCSSc2ncccc2
• InChI: 1S/C24H37N5O3S3/c30-20(10-4-3-9-19-23-18(17-33-19)28-24(32)29-23)25-13-6-1-2-7-14-26-21(31)12-16-34-35-22-11-5-8-15-27-22/h5,8,11,15,18-19,23H,1-4,6-7,9-10,12-14,16-17H2,(H,25,30)(H,26,31)(H2,28,29,32)/t18-,19-,23-/m0/s1
• Clé InChI: QLPHBNRMJLFRGO-YDHSSHFGSA-N

Description

Actions biochimiques/physiologiques

Biotin-HPDP (HPDP-Biotin) is a membrane-permeable and reversible biotinylating reagent that is used to biotinylate target proteins via covalent disulfide bond (-S-S-) formation with free sulfhydryl (-SH) groups. The biotin-tagged proteins can then be subjected to affinity labeling or isolation/purification using avidin conjugates or beads. Unlike tranditonal biotinylation methods, Biotin-HPDP tag can be removed with reducing agents such as dithiothreitol (DTT) without the need of harsh reagents to dissociate the high affinity interaction between avidin and biotin.

Membrane-permeable, reversible biotinylating reagent for affinity labeling and isolation of proteins.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable