SML0476

Rabeprazole sodium

≥98% (HPLC)

• Synonyme(s) : 2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole, Pariprazole
• Formule empirique (notation de Hill): C₁₈H₂₀N₃O₃S · Na
• Numéro CAS: 117976-90-6
• Poids moléculaire : 381.42
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825431
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: H₂O: 10 mg/mL (clear solution)
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: [Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C
• InChI: 1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
• Clé InChI: KRCQSTCYZUOBHN-UHFFFAOYSA-N
• Informations sur le gène: human ... ATP4A(495) , ATP4B(496)

Description

Application

Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.

Actions biochimiques/physiologiques

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H413
• Conseils de prudence: P264 - P270 - P273 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 4
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable