SMB01042

Allocryptopin

≥90% (LC/MS-ELSD)

• Synonyme(s) : β-Allocryptopine, γ-Homochelidonine, Fagarine I
• Formule empirique (notation de Hill): C₂₁H₂₃NO₅
• Numéro CAS: 24240-04-8
• Poids moléculaire : 369.41
• Numéro MDL: MFCD00022318
• Code UNSPSC : 12352205
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: plant
• Pureté: ≥90% (LC/MS-ELSD)
• Forme: solid
• Poids mol.: 369.41
• Solubilité: water: slightly soluble
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Température de stockage: −20°C
• InChI: 1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3
• Clé InChI: HYBRYAPKQCZIAE-UHFFFAOYSA-N

Description

Description générale

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Actions biochimiques/physiologiques

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

Caractéristiques et avantages

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable