SAB5700454

Anti-Phospho-FLNA-S2152 antibody produced in rabbit

• Synonyme(s) : ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FLNA, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 280
• Espèces réactives: rat, mouse, human
• Concentration: 1.7 mg/ml
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: P21333
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer2152)
• Informations sur le gène: human ... FLNA(2316)

Description

Description générale

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Immunogène

A synthetic phosphorylated peptide around S2152 of human FLNA (NP_001104026.1).

Forme physique

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Stockage et stabilité

Store at -20℃. Avoid freeze / thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable