SAB4504254

Anti-phospho-Kv1.3/KCNA3 (pTyr¹³⁵) antibody produced in rabbit

affinity isolated antibody

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 58 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P22001
• Numéro d'accès UniProt: P22001
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr135)
• Informations sur le gène: human ... KCNA3(3738)

Description

Description générale

The voltage-dependent potassium channel (Kv1.3/KCNA3) is expressed in the nervous and immune systems. This gene is located on human chromosome 1p13.

Immunogène

The antiserum was produced against synthesized peptide derived from human Kv1.3/KCNA3 around the phosphorylation site of Tyr135.

Immunogen Range: 101-150

Actions biochimiques/physiologiques

The voltage-dependent potassium channel (Kv1.3/KCNA3) plays a major role in setting the resting membrane potential, cell proliferation, apoptosis and volume regulation. This protein participates in immunomodulation of autoreactive effector and memory T cell-mediated autoimmune diseases. KCNA3 is required for T-cell proliferation and activation.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable