SAB4300668

Anti-Synpr antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-synaptophysin
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~37 kDa
• Espèces réactives: mouse, human, rat
• Concentration: 1 mg/mL
• Technique(s): western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (G-P-T-S-F)
• Numéro d'accès NCBI: NM_023974.1
• Numéro d'accès UniProt: Q8TBG9
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: rat ... Synpr(66030)

Description

Description générale

The antibody detects endogenous levels of total synaptophysin 2 protein.

Immunogène

Peptide sequence around aa. 257-261 (G-P-T-S-F), according to the protein NP_076464.1

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable