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Principaux documents

SAB3500370

Sigma-Aldrich

Anti-TRBP1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-TAR RNA binding protein 1, Anti-TARBP1, Anti-TRP-1, Anti-TRP-185

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About This Item

Numéro MDL:
MFCD03097340
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Conjugué:
unconjugated
application:
ELISA (i)
WB
Clone:
polyclonal
Espèces réactives:
human, mouse
citations:
4
Technique(s):
indirect ELISA: suitable
western blot: suitable

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human, mouse

Technique(s)

indirect ELISA: suitable
western blot: suitable

Numéro d'accès NCBI

NP_005637

Numéro d'accès UniProt

Q13395

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... TARBP1(6894)

Description générale

The gene TARBP1 (TAR (HIV-1) RNA binding protein 1) is mapped to human chromosome 1q42.2. The protein has dsRBDs (double stranded RNA binding domains), a KR motif in the dsRBD2 and a Medipal domain.

Immunogène

TRBP1 antibody was raised against a 17 amino acid peptide from near the center of human TRBP1.

Actions biochimiques/physiologiques

TARBP1 (TAR (HIV-1) RNA binding protein 1) binds strongly to the small hairpin trans-activation responsive (TAR) RNA of HIV (human immunodeficiency virus)-1. It might have a role in disengaging RNA polymerase II from HIV-1 TAR RNA. In addition, it is also a part of the RNA-induced silencing complex (RISC). It interacts with Dicer and helps in processing of pre-microRNAs. TARBP1 also participates in other cellular functions, such as protein synthesis, RNA post-translational modifications, cellular proliferation, gene expression and stress-associated cellular processes.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Liaison

The action of this antibody can be blocked using blocking peptide SBP3500370.

Forme physique

Supplied in PBS with 0.02% sodium azide.

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Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
40110604

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Robert D Beech et al.
Alcoholism, clinical and experimental research, 38(11), 2743-2753 (2014-11-26)
Alterations in stress-related gene expression may play a role in stress-related drinking and the risk of alcohol dependence. Microarrays were used to measure changes in gene expression in peripheral blood in nonsmoking, social drinking subjects exposed to 3 types of
Orla M Keane et al.
BMC genomics, 7, 42-42 (2006-03-07)
Gastrointestinal nematodes constitute a major cause of morbidity and mortality in grazing ruminants. Individual animals or breeds, however, are known to differ in their resistance to infection. Gene expression profiling allows us to examine large numbers of transcripts simultaneously in
F Wu-Baer et al.
The EMBO journal, 14(23), 5995-6009 (1995-12-01)
Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element located downstream of the transcription initiation site known as TAR. To characterize cellular factors that bind to TAR RNA and are involved in the
Sandrine Cornaz-Buros et al.
Cancer research, 74(22), 6610-6622 (2014-09-28)
Plasticity in cancer stem-like cells (CSC) may provide a key basis for cancer heterogeneity and therapeutic response. In this study, we assessed the effect of combining a drug that abrogates CSC properties with standard-of-care therapy in a Ewing sarcoma family

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