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Key Documents

SAB2500965

Sigma-Aldrich

Anti-SNAP25 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-FLJ23079, Anti-HGNC:11132, Anti-SNAP, Anti-Synaptosomal-associated protein

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

rat, canine, human, mouse

Technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SNAP25(6616)

Description générale

Synaptosome associated protein 25 (SNAP25) is a component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. It is expressed in pancreatic endocrine cells. The gene encoding this protein is localized on human chromosome 20p12.2.

Immunogène

Peptide with sequence C-DEANQRATKMLGSG from the C Terminus of the protein sequence according to NP_003072.2; NP_570824.1.

Actions biochimiques/physiologiques

Synaptosome associated protein 25 (SNAP25) has a role in vesicle mobilization, exocytosis and may have a role in fusion of synaptic vesicles. It is involved in modulating the activity of potassium voltage gated (Kv) 2.1 channels. SNAP25 has been associated with attention-deficit/hyperactivity disorder (ADHD).

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Synaptosome-Associated Protein 25 (SNAP25) Gene Association Analysis Revealed Risk Variants for ASD, in Iranian Population.
Safari MR
Journal of Molecular Neuroscience (2017)
SNAP25 is associated with schizophrenia and major depressive disorder in the Han Chinese population.
Wang Q
The Journal of Clinical Psychiatry (2015)
Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma.
Huang CJ
International Journal of Molecular Medicine (2017)
Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients.
Al-Daghri
Journal of Diabetes Research (2016)
Masanori Itakura et al.
Biochemical and biophysical research communications, 447(2), 311-314 (2014-04-10)
Recent reports indicate that interruption of acetylcholine release by intrastriatal injection of botulinum neurotoxin type A (BoNT/A) in a rat Parkinson's disease model reduces pathogenic behavior without adverse side effects such as memory dysfunction. Current knowledge suggests that BoNT/A subtype

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