SAB1306277

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonyme(s) : BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein, Osteocalcin
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Forme d'anticorps: IgG fraction of antiserum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 10963 Da
• Espèces réactives: human
• Technique(s): immunohistochemistry: 1:50-1:100; western blot: 1:1000
• Numéro d'accès NCBI: NP_954642.1
• Numéro d'accès UniProt: P02818
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BGLAP(632)

Description

Description générale

Bone γ-carboxyglutamate protein (BGLAP) or osteocalcin (OCN) is a non-collagenous bone matrix protein expressed by osteoblasts. It possesses a Gla (γ-carboxyglutamate) domain. The gene encoding OCN is localized on human chromosome 1q22.

Application

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit has been used in western blotting and immnuohistochemistry.

Actions biochimiques/physiologiques

Bone γ-carboxyglutamate protein (BGLAP) regulates osteogenic differentiation of mesenchymal stromal cells. It has a role in bone turnover and mineralization. The protein also has a role in energy metabolism. BGLAP may act as a mediator between glucose metabolism and bone tissue.

Forme physique

Supplied in PBS with 0.09% (W/V) sodium azide

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable