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P9180

Sigma-Aldrich

Procaterol hydrochloride

Synonyme(s) :

erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone

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About This Item

Formule empirique (notation de Hill):
C16H22N2O3 · HCl
Numéro CAS:
62929-91-3
Poids moléculaire :
326.82
Numéro CE :
263-763-0
Numéro MDL:
MFCD04221378
Code UNSPSC :
12352202
ID de substance PubChem :
24899017
Nomenclature NACRES :
NA.77

Forme

powder

Température de stockage

2-8°C

Chaîne SMILES 

Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12

InChI

1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1

Clé InChI

AEQDBKHAAWUCMT-CVHDTDHSSA-N

Description générale

Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.

Actions biochimiques/physiologiques

β2-adrenoceptor agonist; bronchodilator.

Caractéristiques et avantages

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Guixin Li et al.
The Analyst, 134(7), 1396-1404 (2009-06-30)
A novel space- and time-resolved photo-induced chemiluminescence (PICL) analytical method was developed based on the photocatalysis of the Co2+-doped TiO2 nanoparticles. The PICL reaction procedure under the photocatalysis of Co2+-doped TiO2 nanoparticles was investigated using cyclic voltammetry and potentiometry. Meanwhile
Mutsuo Yamaya et al.
European journal of pharmacology, 650(1), 431-444 (2010-10-14)
β(2) agonists reduce the frequency of exacerbations in patients with bronchial asthma and chronic obstructive pulmonary disease caused by respiratory virus infection. β(2) agonists reduce the production of pro-inflammatory cytokines. However, the inhibitory effects of β(2) agonists on the infection
Sébastien Banquet et al.
Cellular signalling, 23(7), 1136-1143 (2011-03-10)
Activation of the β₂-adrenoceptor (β₂-AR) elicits an endothelial nitric oxide synthase (eNOS)-dependent relaxation in mouse pulmonary artery, which, contrary to the muscarinic receptor-dependent relaxation, is preserved in hypoxic pulmonary arterial hypertension. We therefore characterized the signaling pathways underlying the β₂-AR-mediated
Jin Sakamoto et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31(7), 773-779 (2012-04-27)
It is a matter of great importance in a donation after cardiac death to attenuate ischemia-reperfusion injury (IRI) related to the inevitable warm ischemic time. Donor dogs were rendered cardiac-dead and left at room temperature. The dogs were allocated into
F Preitner et al.
British journal of pharmacology, 124(8), 1684-1688 (1998-10-02)
The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor knockout and wild type
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