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Key Documents

P3440

Sigma-Aldrich

Polyoxyethylene (40) stearate

Synonyme(s) :

Myrj 52

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About This Item

Numéro CAS:
9004-99-3
Numéro MDL:
MFCD00148007
Code UNSPSC :
12161900
Nomenclature NACRES :
NA.25

Description

non-ionic

Forme

powder

Application(s)

detection

InChI

1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3

Clé InChI

RFVNOJDQRGSOEL-UHFFFAOYSA-N

Description générale

Polyoxyethylene (40) stearate is a neutral surfactant.

Application

Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. It has also been used in a study to investigate its effects on multidrug resistance (MDR).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Lingying Luo et al.
The AAPS journal, 9(3), E329-E335 (2008-01-04)
Multidrug resistance (MDR) is one of the major obstacles limiting the efficacy of cancer chemotherapy. Identification of new and effective MDR reversal agents is needed. In this study, the effects of polyoxyethylene 40 stearate (PS40) on MDR were evaluated via
Michalakis Savva et al.
Colloids and surfaces. A, Physicochemical and engineering aspects, 325(1-2), 1-6 (2009-07-18)
The feasibility of a method based on mass preservation [G. Schwarz, J. Zhang, Chem. Phys. Lipids, 110 (2001) 35-45] to determine the solubility of Cholesterol in water from monomolecular films on air/water interface was investigated. Using a mass balance equation
Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450.
Zhu, S., et al.
European Journal of Pharmaceutical Sciences, 37, 8-8 (2009)
Klaus Raith et al.
International journal of pharmaceutics, 319(1-2), 1-12 (2006-05-30)
The in-depth characterization of excipients is a prerequisite for their safe application in pharmaceutical products. In case of surfactants, this task can be a challenge, since many industrial products are mixtures of variable composition. In this work, mass spectrometric methods
Hong Yuan et al.
Colloids and surfaces. B, Biointerfaces, 60(2), 174-179 (2007-07-28)
Nanostructured lipid carriers (NLC) made from mixtures of solid and spatially incompatible liquid lipids were prepared by melt-emulsification. Their drug loading capacity and releasing properties of progesterone were compared with those of solid lipid nanoparticles (SLN), and the NLC prepared
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