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Key Documents

O1391

Sigma-Aldrich

Oil Red O solution

0.5% in isopropanol

Synonyme(s) :

Solvent Red 27, Sudan Red 5B

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About This Item

Formule empirique (notation de Hill):
C26H24N4O
Numéro CAS:
Poids moléculaire :
408.49
Numéro CE :
Code UNSPSC :
12171500
Nomenclature NACRES :
NA.47

Forme

liquid

Niveau de qualité

Concentration

0.5% in isopropanol

Couleur

dark red

εmax

0.20-0.50 at 510-517 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

InChI

1S/C26H24N4O/c1-16-9-10-17(2)22(13-16)27-28-23-14-19(4)24(15-18(23)3)29-30-26-21-8-6-5-7-20(21)11-12-25(26)31/h5-15,29H,1-4H3/b28-27?,30-26-

Clé InChI

HJAYEODIXUYVIC-LTFAAIOASA-N

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Description générale

Oil Red O stains lipid materials and imparts red-orange color to the lipids. It also marks vacuoles, particularly observed in ALL-L3 (acute lymphoblastic leukemia) or Burkitt′s lymphoma/leukemia. Oil Red O staining is done on fresh samples, as alcohol fixation removes lipids.

Application

Oil red O solution has been used to stain neutral lipids and adipocytes and to visualize fat droplets in fibroblasts.
Oil red O is a lysochrome (fat-soluble dye) diazo dye used for staining of neutral triglycerides and lipids on frozen sections and some lipoproteins on paraffin sections. In histology, a supersaturated solution of oil red O in isopropanol may be used to stain fat in tissue.

Pictogrammes

FlameExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

53.6 °F - closed cup

Point d'éclair (°C)

12.0 °C - closed cup


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Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells.
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Breast Cancer Research and Treatment, 141(2), 317-324 (2013)
Directly reprogramming fibroblasts into adipogenic, neurogenic and hepatogenic differentiation lineages by defined factors.
Wu W, et al.
Experimental and Therapeutic Medicine, 13(6), 2685-2690 (2017)
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Frontiers in molecular neuroscience, 10, 337-337 (2017-11-09)
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