MAK532

Nitric Oxide Synthase (NOS) Assay Kit

sufficient for 100 colorimetric tests

• Code UNSPSC : 12161503
• Nomenclature NACRES : NA.84

Propriétés

• Niveau de qualité: 100
• Application(s): pharmaceutical
• Méthode de détection: colorimetric
• Maladie(s) pertinente(s): cardiovascular diseases; immunological diseases; aging/geriatric diseases; cancer
• Conditions d'expédition: wet ice
• Température de stockage: −20°C

Description

Description générale

Nitric oxide (NO) is a reactive radical that plays an important role in many key physiological functions. NO, an oxidation product of arginine by nitric oxide synthase (NOS), is involved in host defense and development, activation of regulatory proteins and direct covalent interaction with functional biomolecules.

Caractéristiques et avantages

• Linear detection range: 0.25 - 25 U/L

Adéquation

The kit is suitable for the determination of nitric oxide synthase activity in biological samples, as well as for studying the effects of drugs on nitric oxide synthase activity.

Principe

The Nitric Oxide Synthase (NOS) Assay Kit nvolves two steps: a NOS reaction step during which NO is produced followed by an NO detection step. Since the NO generated by NOS is rapidly oxidized to nitrite and nitrate, the NO production is measured following reduction of nitrate to nitrite using an improved Griess method. The procedure is simple and the time required for sample pretreatment and assay is reduced to as short as 40 minutes.

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H290,H302,H314,H411
• Conseils de prudence: P234 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3