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MAK077

Sigma-Aldrich

Uric Acid Assay Kit

sufficient for 100 colorimetric or fluorometric tests

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric or fluorometric tests

Méthode de détection

colorimetric
fluorometric

Maladie(s) pertinente(s)

endocrinological disorders, diabetes; cardiovascular diseases; rheumatological diseases; genitourinary disorders

Température de stockage

−20°C

Description générale

In humans and primates, uric acid is the end product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and excreted in urine. High serum levels of uric acid, hyperuricemia, are associated with insulin resistance, cardiovascular disease, and gout. The mechanisms leading to hyperuricemia are typically either increased uric acid production or decreased urine excretion. Increased serum uric acid may be a marker of renal disease.

Application

Uric Acid Assay Kit has been used
  • to determine the uric acid content in human adipose-derived stem cell culture supernatant
  • to measure serum uric acid level in order to analyse kidney function in rat models
  • to determine the uric acid concentration in serum and to study the e antiinflammatory effects of sunflower head ethanol extract in rats
  • in quantitative analysis of uric acid degradation

Adéquation

Suitable for detecting uric acid in biological samples such as serum and urine. Pretreatment of samples is not required

Principe

In this assay, Uric Acid concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the Uric Acid present.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

06693

Timestrip Plus™ -20 °C

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H334,H412

Conseils de prudence

P261 - P273 - P284 - P501

Classification des risques

Aquatic Chronic 3 - Resp. Sens. 1

Code de la classe de stockage

10 - Combustible liquids

Point d'éclair (°F)

188.6 °F - closed cup

Point d'éclair (°C)

87 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number
7M29K06080
7G12K06080
7B22K06080
6E29K06080
6D23K06080

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Stephanie A Terry et al.
Journal of animal science, 96(9), 3863-3877 (2018-09-01)
Ruminants play an important role in food security, but there is a growing concern about the impact of cattle on the environment, particularly regarding greenhouse gas emissions. The objective of this study was to examine the effect of humic substances
Stephanie A Terry et al.
Frontiers in veterinary science, 6, 308-308 (2019-10-15)
The objective of this study was to examine the effect of a pine enhanced biochar (EB) on rumen fermentation, apparent total tract digestibility, methane (CH4) emissions, and the rumen and fecal microbiome of Angus × Hereford heifers fed a barley
A Role for Uric Acid in the Progression of Renal Disease.
Kang, D.-H
Journal of the American Society of Nephrology, 12, 2888-2897 (2002)
Anti-gouty arthritis and antihyperuricemia effects of sunflower (Helianthus annuus) head extract in gouty and hyperuricemia animal models.
Li L, et al.
BioMed Research International, 2017 (2017)
Effect of humic substances on rumen fermentation, nutrient digestibility, methane emissions, and rumen microbiota in beef heifers.
Terry S A, et al.
Journal of Animal Science (2018)
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