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M3534

Sigma-Aldrich

Anti-Mouse IgG (Fc specific) antibody produced in goat

2.0 mg/mL, affinity isolated antibody

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About This Item

Numéro MDL:
MFCD00162625
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Concentration

2.0 mg/mL

Technique(s)

indirect ELISA: 1:15,000

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

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Catégories apparentées

Description générale

IgG subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.

Immunogène

Mouse IgG, Fc fragment

Application

Anti-Mouse IgG (Fc specific) antibody has been used in:
  • enzyme linked immunosorbent assay (ELISA)
  • Ouchterlony double diffusion
  • anti-drug antibody immunoassay
  • immunoelectrophoresis

Actions biochimiques/physiologiques

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice

Autres remarques

Antibody adsorbed with human IgG and rat serum proteins

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Notes préparatoires

Adsorbed to reduce background with human or rat samples.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Integrating molecular detection and response to create self-signalling antibodies
Randle B, et al.
Biochemical and Biophysical Research Communications, 324(2), 504-510 (2004)
Universal immunoassay applied during early development of large molecules to understand impact of immunogenicity on biotherapeutic exposure
Bautista AC, et al.
The APPS Journal, 14(4), 843-849 (2012)
N Ban et al.
British journal of cancer, 101(2), 363-371 (2009-06-11)
The essential aetiology of radiation-induced acute myeloid leukaemia (AML) in mice is the downregulation of the transcription factor PU.1. The causative mutation of the PU.1-endocing Sfpi1 gene consists mostly of C:G to T:A transitions at a CpG site and is
Nathan H Joh et al.
Journal of pharmaceutical sciences, 109(1), 845-853 (2019-10-20)
Silicone oil is a lubricant for prefilled syringes (PFS), a common primary container for biotherapeutics. Silicone oil particles (SiOP) shed from PFS are a concern for patients due to their potential for increased immunogenicity and therefore also of regulatory concern.
Development and validation of a standardized ELISA for the detection of soluble Fc-epsilon-RI in human serum
Lexmond W, et al.
Journal of Immunological Methods, 373(1-2), 192-199 (2011)
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