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Autres documents

M2696

Sigma-Aldrich

Metyrapone

≥98% (HPLC), solid

Synonyme(s) :

Su-4885

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About This Item

Formule empirique (notation de Hill):
C14H14N2O
Numéro CAS:
54-36-4
Poids moléculaire :
226.27
Numéro Beilstein :
163023
Numéro CE :
200-206-2
Numéro MDL:
MFCD00006397
Code UNSPSC :
51111800
ID de substance PubChem :
329817949
Nomenclature NACRES :
NA.77

Stérilité

non-sterile

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

solid

Technique(s)

toxicology assay: suitable

Pf

52-55 °C (lit.)

Solubilité

H2O: <2 mg/mL
DMSO: >20 mg/mL

Auteur

Novartis

Conditions d'expédition

ambient

Température de stockage

room temp

Chaîne SMILES 

CC(C)(c1cccnc1)C(=O)c2cccnc2

InChI

1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3

Clé InChI

FJLBFSROUSIWMA-UHFFFAOYSA-N

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Actions biochimiques/physiologiques

Metyrapone is a glucocorticoid synthesis inhibitor; a standard in assessing adrenal gland function especially in response to stress, as well as pituitary gland function. In addition to acting as a glucocorticoid synthesis inhibitor, Metyrapone also inhibits cytochrome P450-mediated prostaglandin ω/ω-1 hydroxylase activity and impairs learning and memory. Data shows results in activation of the sleep EEG and a robust decrease in quantitative delta sleep.

Caractéristiques et avantages

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 - H315 - H319 - H335

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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