I9534

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in rat

clone 122404, purified immunoglobulin, lyophilized powder

• Synonyme(s) : Anti-Igf-II, Anti-Igf2, Anti-Mpr, Anti-Peg2
• Code UNSPSC : 51111800
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rat
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 122404, monoclonal
• Forme: lyophilized powder
• Espèces réactives: mouse
• Technique(s): capture ELISA: 2-8 μg/mL; western blot: 1-2 μg/mL
• Isotype: IgG2a
• Numéro d'accès UniProt: P09535
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Igf2(16002)

Description

Immunogène

purified, E. coli-derived recombinant mouse insulin-like growth factor-II.

Actions biochimiques/physiologiques

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.