Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

Autres documents

GW21181

Sigma-Aldrich

Anti-VEGFR-2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Vascular endothelial growth factor receptor 2

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

chicken

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

rat, mouse, human

Fabricant/nom de marque

Genway 15-288-21181

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

P35968

Numéro d'accès UniProt

P35968

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... KDR(3791)

Immunogène

Immunogen Sequence: GI # 9087218, sequence 51-119
Recombinant vascular endothelial growth factor receptor 2

Application

Anti-VEGFR-2 antibody produced in chicken is suitable for immunohistochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase, VEGFR-2) is a VEGF receptor and is encoded by KDR gene in humans. It plays a crutial role in controlling endothelial trafficking activity and is involved in phosphotyrosine phosphatase 1b (PTP1b). PTP1b acts as a key regulator of endothelial VEGFR2 signaling and plays a critical role in regulation of the extent of vascular tree formation. VEGFR2 may be associated with gout and hyperuricaemia risks in Malays.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Vous ne trouvez pas le bon produit ?  

Essayez notre Outil de sélection de produits.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Yap W K Roseline et al.
Malaysian journal of nutrition, 18(3), 307-317 (2012-12-01)
Gout and hyperuricaemia attributed to genetic and lifestyle factors have been associated with several chronic diseases. This study aimed to determine the association and interaction effects between vascular endothelial growth factor receptor-2 (VEGFR-2) gene polymorphisms (rs1870377 and rs2071559) and dietary
PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.
Lanahan AA, Lech D, Dubrac A, et al.
Circulation, 130(11), 902-909 (2014)
Giuseppe Di Stolfo et al.
Clinical hemorheology and microcirculation, 72(1), 23-38 (2018-10-16)
Carotid stenting stimulates intimal proliferation through platelet and stem cell activation. The aim of this study is to evaluate whether the administration before or after carotid stenting of clopidogrel loading dose may play a role on circulating endothelial progenitor cells
Soumaya Hachana et al.
British journal of pharmacology, 177(9), 1949-1966 (2019-12-29)
Age-related macular degeneration (AMD) is a complex neurodegenerative disease treated by anti-VEGF intravitreal injections. As inflammation is potentially involved in retinal degeneration, the pro-inflammatory kallikrein-kinin system is a possible alternative pharmacological target. Here, we investigated the effects of anti-VEGF and
G Ji et al.
The bone & joint journal, 101-B(7_Supple_C), 108-114 (2019-07-02)
It is increasingly appreciated that coordinated regulation of angiogenesis and osteogenesis is needed for bone formation. How this regulation is achieved during peri-implant bone healing, such as osseointegration, is largely unclear. This study examined the relationship between angiogenesis and osteogenesis
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique