Accéder au contenu
Merck
Toutes les photos(1)

Principaux documents

Voir toute la documentation

GW10801F

Sigma-Aldrich

Anti-RNASE1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-RNS1, Anti-Ribonuclease pancreatic

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

chicken

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human

Fabricant/nom de marque

Genway 15-288-10801F

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_002924.1

Numéro d'accès UniProt

P07998

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... RNASE1(6035)

Immunogène

Immunogen Sequence: GI # 4506547, sequence 1-156
Recombinant pancreatic ribonuclease

Application

Anti-RNASE1 antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

Actions biochimiques/physiologiques

RNASE1 encodes a protein that is a subset of the ribonuclease A superfamily. It is a pancreatic type of secretory ribonuclease. It acts on the 3′-side of pyrimidine bases and cleaves internal phosphodiester RNA bonds. It is a monomer and preferentially acts on ds-RNA over ss-RNA. Human RNAse I is involved in the digestion of dietary RNA, regulation of vascular homeostasis and inactivation of the HIV. It is also involved in the activation of immature dendritic cells and induction of cytokine production.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Vous ne trouvez pas le bon produit ?  

Essayez notre Outil de sélection de produits.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Md Tabish Rehman et al.
PloS one, 6(3), e17159-e17159 (2011-03-17)
Human pancreatic ribonuclease (HPR), a member of RNase A superfamily, has a high activity on double stranded (ds) RNA. By virtue of this activity HPR appears to be involved in the host-defense against pathogenic viruses. To delineate the mechanism of
R Jeremy Johnson et al.
Journal of molecular biology, 368(2), 434-449 (2007-03-14)
The ribonuclease inhibitor protein (RI) binds to members of the bovine pancreatic ribonuclease (RNase A) superfamily with an affinity in the femtomolar range. Here, we report on structural and energetic aspects of the interaction between human RI (hRI) and human
K E Kövér et al.
Journal of molecular biology, 379(5), 953-965 (2008-05-23)
Human pancreatic ribonuclease (RNase 1) is expressed in many tissues; has several important enzymatic and biological activities, including efficient cleavage of single-stranded RNA, double-stranded RNA and double-stranded RNA-DNA hybrids, digestion of dietary RNA, regulation of vascular homeostasis, inactivation of the
Victoria J Mar et al.
Pigment cell & melanoma research, 27(6), 1117-1125 (2014-07-22)
Activating mutations in the GTPase RAC1 are a recurrent event in cutaneous melanoma. We investigated the clinical and pathological associations of RAC1(P29S) in a cohort of 814 primary cutaneous melanomas with known BRAF and NRAS mutation status. The RAC1(P29S) mutation

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique